

8 experts have a pick on San Francisco 49ers vs Arizona Cardinals
We predict San Francisco 49ers
Betting Odds
Betting odds imply a 77% chance for San Francisco 49ers
Professional handicappers have analyzed this game
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San Francisco 49ers are favored over Arizona Cardinals based on the latest moneyline (San Francisco 49ers -400, Arizona Cardinals +315).
San Francisco 49ers -7.50, Arizona Cardinals 7.50. Spread reflects the projected margin between the two teams.
The total (over/under) is 48.50. Over 48.50 or under 48.50 wins respectively.
San Francisco 49ers vs Arizona Cardinals is scheduled for Sep 27 at 04:05 PM ET.