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  1. Home/
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  3. NFL/
  4. Colts vs Titans

Indianapolis Colts vs Tennessee TitansNFL Picks, Prediction & Odds • Oct 18 • 01:00 PM

Indianapolis Colts logo

Colts

0-0
Starting Now
Tennessee Titans logo

Titans

🎯Expert Handicappers

Top-performing experts with proven track records

Sports Hub - FREE PICKS

Sports Hub - FREE PICKS

70% Win Rate
Frankie the Fan

Frankie the Fan

70% Win Rate
Wise Guy Plays

Wise Guy Plays

70% Win Rate
Pro Picks - Andrew

Pro Picks - Andrew

70% Win Rate
Calvin King

Calvin King

70% Win Rate
Sports Hub - FREE PICKS

Sports Hub - FREE PICKS

70% Win Rate
Frankie the Fan

Frankie the Fan

70% Win Rate
Wise Guy Plays

Wise Guy Plays

70% Win Rate
Pro Picks - Andrew

Pro Picks - Andrew

70% Win Rate
Calvin King

Calvin King

70% Win Rate

Our Prediction

Indianapolis Colts logoColts72%
28%TitansTennessee Titans logo
Indianapolis Colts logo
Colts
2-2American Football Conference #15
VS
Tennessee Titans logo
Titans
0-4American Football Conference #30
Confidence
High

We predict Indianapolis Colts

Key Factors

Betting Odds

Betting odds imply a 63% chance for Colts

Season Record

Colts is 2-2 this season

Standings Position

Colts ranked #15 in standings

Head-to-Head

Colts leads the recent series 2-0

Team Comparison

Indianapolis Colts logoColts
TitansTennessee Titans logo
Offense
25.5
PPG
13.8
Defense
26.0
Opp PPG
20.8
General
2-2
Record
0-4
50.0%
Win %
0.0%
#15
Ranking
#30

Head-to-Head

Last 2 meetings

Indianapolis Colts logo
2
Colts
Tennessee Titans logo
0
Titans
100%

Recent Matchups

Oct 26, 2025
38-14
Colts
Sep 21, 2025
41-20
Colts

H2H Averages (Last 2 Games)

39.5
17.0
Colts AvgAvg ScoreTitans Avg

Betting Odds

Indianapolis Colts logoColts
TitansTennessee Titans logo
Spread
-3.50
-110
3.50
-110
Moneyline
-192
FAV
+160
Total (O/U 48.50)
Over
-110
Under
-110

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Frequently asked questions

Who is favored to win Indianapolis Colts vs Tennessee Titans?▾

Indianapolis Colts are favored over Tennessee Titans based on the latest moneyline (Colts -192, Titans +160).

What is the point spread for Indianapolis Colts vs Tennessee Titans?▾

Colts -3.50, Titans 3.50. Spread reflects the projected margin between the two teams.

What is the over/under for Indianapolis Colts vs Tennessee Titans?▾

The total (over/under) is 48.50. Over 48.50 or under 48.50 wins respectively.

When is Indianapolis Colts vs Tennessee Titans?▾

Indianapolis Colts vs Tennessee Titans is scheduled for Oct 18 at 01:00 PM ET.

More NFL picks

  • Los Angeles Rams vs Buffalo Bills
    Mon, Oct 12
  • Denver Broncos vs Seattle Seahawks
    Thu, Oct 15
  • Jacksonville Jaguars vs Houston Texans
    Sun, Oct 18
  • Atlanta Falcons vs Chicago Bears
    Sun, Oct 18
  • New England Patriots vs New York Jets
    Sun, Oct 18
  • New York Giants vs New Orleans Saints
    Sun, Oct 18
See all NFL picks →

Betting Odds

Indianapolis Colts logoColts
TitansTennessee Titans logo
Spread
-3.50
-110
3.50
-110
Moneyline
-192
FAV
+160
Total (O/U 48.50)
Over
-110
Under
-110
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21+Bet responsibly. Picks are for entertainment — gambling involves risk.

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Please gamble responsibly. If you have a gambling problem, please visit ncpgambling.org