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  1. Home/
  2. Picks/
  3. NFL/
  4. Buffalo Bills vs Detroit Lions

Buffalo Bills vs Detroit LionsNFL Picks, Prediction & Odds • Sep 17 • 08:15 PM

Buffalo Bills logo

Buffalo Bills

0-0
Starting Now
Detroit Lions logo

Detroit Lions

2Picks

Experts Betting This Game

2 experts have a pick on Buffalo Bills vs Detroit Lions

View Expert Picks
Kyle Parker

Kyle Parker

70% Win Rate
Pick on this game
Premium pick +100Unlock
Wise Guy Plays

Wise Guy Plays

30% Win Rate
Pick on this game
Premium pick +100Unlock
Kyle Parker

Kyle Parker

70% Win Rate
Pick on this game
Premium pick +100Unlock
Wise Guy Plays

Wise Guy Plays

30% Win Rate
Pick on this game
Premium pick +100Unlock

Our Prediction

Buffalo Bills logoBuffalo Bills67%
33%Detroit LionsDetroit Lions logo
Buffalo Bills logo
Buffalo Bills
VS
Detroit Lions logo
Detroit Lions
Confidence
Low

We predict Buffalo Bills

Key Factors

Betting Odds

Betting odds imply a 67% chance for Buffalo Bills

2

Expert Picks Available

Professional handicappers have analyzed this game

Betting Odds

Buffalo Bills logoBuffalo Bills
Detroit LionsDetroit Lions logo
Spread
-4.50
-110
4.50
-110
Moneyline
-227
FAV
+190
Total (O/U 54.50)
Over
-110
Under
-110

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Frequently asked questions

Who is favored to win Buffalo Bills vs Detroit Lions?▾

Buffalo Bills are favored over Detroit Lions based on the latest moneyline (Buffalo Bills -227, Detroit Lions +190).

What is the point spread for Buffalo Bills vs Detroit Lions?▾

Buffalo Bills -4.50, Detroit Lions 4.50. Spread reflects the projected margin between the two teams.

What is the over/under for Buffalo Bills vs Detroit Lions?▾

The total (over/under) is 54.50. Over 54.50 or under 54.50 wins respectively.

When is Buffalo Bills vs Detroit Lions?▾

Buffalo Bills vs Detroit Lions is scheduled for Sep 17 at 08:15 PM ET.

2

Expert Picks Available

Professional handicappers have analyzed this game

Betting Odds

Buffalo Bills logoBuffalo Bills
Detroit LionsDetroit Lions logo
Spread
-4.50
-110
4.50
-110
Moneyline
-227
FAV
+190
Total (O/U 54.50)
Over
-110
Under
-110
GameAdvisers logo

Expert sports betting picks and predictions

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21+Bet responsibly. Picks are for entertainment — gambling involves risk.

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Please gamble responsibly. If you have a gambling problem, please visit ncpgambling.org