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  1. Home/
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  3. MLB/
  4. Houston Astros vs Arizona Diamondbacks

Houston Astros vs Arizona DiamondbacksMLB Picks, Prediction & Odds • Sep 4 • 08:11 PM

Houston Astros logo

Houston Astros

0-0
Starting Now
Arizona Diamondbacks logo

Arizona Diamondbacks

16Picks

Experts Betting This Game

16 experts have a pick on Houston Astros vs Arizona Diamondbacks

View Expert Picks
Randall Dickelman

Randall Dickelman

30% Win Rate
Pick on this game
Premium pick +100Unlock
Sports Hub - FREE PICKS

Sports Hub - FREE PICKS

30% Win Rate
Pick on this game
Premium pick +100Unlock
Knup Sports - POTD

Knup Sports - POTD

70% Win Rate
Pick on this game
Premium pick +100Unlock
Kyle Parker

Kyle Parker

70% Win Rate
Pick on this game
Premium pick +100Unlock
Keylor Santos

Keylor Santos

70% Win Rate
Pick on this game
Premium pick +100Unlock
Randall Dickelman

Randall Dickelman

30% Win Rate
Pick on this game
Premium pick +100Unlock
Sports Hub - FREE PICKS

Sports Hub - FREE PICKS

30% Win Rate
Pick on this game
Premium pick +100Unlock
Knup Sports - POTD

Knup Sports - POTD

70% Win Rate
Pick on this game
Premium pick +100Unlock
Kyle Parker

Kyle Parker

70% Win Rate
Pick on this game
Premium pick +100Unlock
Keylor Santos

Keylor Santos

70% Win Rate
Pick on this game
Premium pick +100Unlock

Our Prediction

Houston Astros logoHouston Astros54%
46%Arizona DiamondbacksArizona Diamondbacks logo
Houston Astros logo
Houston Astros
VS
Arizona Diamondbacks logo
Arizona Diamondbacks
Confidence
Low

We predict Houston Astros

Key Factors

Betting Odds

Betting odds imply a 54% chance for Houston Astros

16

Expert Picks Available

Professional handicappers have analyzed this game

Betting Odds

Houston Astros logoHouston Astros
Arizona DiamondbacksArizona Diamondbacks logo
Spread
-1.50
+160
1.50
-185
Moneyline
-130
FAV
+108
Total (O/U 9.00)
Over
+100
Under
-120

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Frequently asked questions

Who is favored to win Houston Astros vs Arizona Diamondbacks?▾

Houston Astros are favored over Arizona Diamondbacks based on the latest moneyline (Houston Astros -130, Arizona Diamondbacks +108).

What is the point spread for Houston Astros vs Arizona Diamondbacks?▾

Houston Astros -1.50, Arizona Diamondbacks 1.50. Spread reflects the projected margin between the two teams.

What is the over/under for Houston Astros vs Arizona Diamondbacks?▾

The total (over/under) is 9.00. Over 9.00 or under 9.00 wins respectively.

When is Houston Astros vs Arizona Diamondbacks?▾

Houston Astros vs Arizona Diamondbacks is scheduled for Sep 4 at 08:11 PM ET.

More MLB picks

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    Fri, Sep 4
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    Fri, Sep 4
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    Fri, Sep 4
  • Miami Marlins vs Chicago Cubs
    Fri, Sep 4
  • New York Mets vs San Francisco Giants
    Fri, Sep 4
See all MLB picks →
16

Expert Picks Available

Professional handicappers have analyzed this game

Betting Odds

Houston Astros logoHouston Astros
Arizona DiamondbacksArizona Diamondbacks logo
Spread
-1.50
+160
1.50
-185
Moneyline
-130
FAV
+108
Total (O/U 9.00)
Over
+100
Under
-120
GameAdvisers logo

Expert sports betting picks and predictions

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© 2026 GameAdvisers. All rights reserved.

21+Bet responsibly. Picks are for entertainment — gambling involves risk.

GameAdvisers may earn a commission from sportsbook partners linked from this site. Picks and editorial content are produced independently of any partnership. Affiliate Disclosure

Please gamble responsibly. If you have a gambling problem, please visit ncpgambling.org