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  1. Home/
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  3. MLB/
  4. Chicago Cubs vs Pittsburgh Pirates

Chicago Cubs vs Pittsburgh PiratesMLB Picks, Prediction & Odds • Sep 11 • 02:21 PM

Chicago Cubs logo

Chicago Cubs

5-1
Starting Now
Pittsburgh Pirates logo

Pittsburgh Pirates

4Picks

Experts Betting This Game

4 experts have a pick on Chicago Cubs vs Pittsburgh Pirates

View Expert Picks
Knup Sports - POTD

Knup Sports - POTD

70% Win Rate
Pick on this game
Premium pick +100Unlock
Skyler Lockheart

Skyler Lockheart

70% Win Rate
Pick on this game
Premium pick +100Unlock
Frankie the Fan

Frankie the Fan

70% Win Rate
Pick on this game
Premium pick +100Unlock
Pro Picks - Ben

Pro Picks - Ben

70% Win Rate
Pick on this game
Premium pick +100Unlock
Knup Sports - POTD

Knup Sports - POTD

70% Win Rate
Pick on this game
Premium pick +100Unlock
Skyler Lockheart

Skyler Lockheart

70% Win Rate
Pick on this game
Premium pick +100Unlock
Frankie the Fan

Frankie the Fan

70% Win Rate
Pick on this game
Premium pick +100Unlock
Pro Picks - Ben

Pro Picks - Ben

70% Win Rate
Pick on this game
Premium pick +100Unlock

Our Prediction

Chicago Cubs logoChicago Cubs64%
36%Pittsburgh PiratesPittsburgh Pirates logo
Chicago Cubs logo
Chicago Cubs
VS
Pittsburgh Pirates logo
Pittsburgh Pirates
Confidence
Low

We predict Chicago Cubs

Key Factors

Betting Odds

Betting odds imply a 64% chance for Chicago Cubs

4

Expert Picks Available

Professional handicappers have analyzed this game

Betting Odds

Chicago Cubs logoChicago Cubs
Pittsburgh PiratesPittsburgh Pirates logo
Spread
-1.50
+102
1.50
-122
Moneyline
-189
FAV
+170
Total (O/U 8.50)
Over
-110
Under
-110

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Frequently asked questions

Who is favored to win Chicago Cubs vs Pittsburgh Pirates?▾

Chicago Cubs are favored over Pittsburgh Pirates based on the latest moneyline (Chicago Cubs -189, Pittsburgh Pirates +170).

What is the point spread for Chicago Cubs vs Pittsburgh Pirates?▾

Chicago Cubs -1.50, Pittsburgh Pirates 1.50. Spread reflects the projected margin between the two teams.

What is the over/under for Chicago Cubs vs Pittsburgh Pirates?▾

The total (over/under) is 8.50. Over 8.50 or under 8.50 wins respectively.

When is Chicago Cubs vs Pittsburgh Pirates?▾

Chicago Cubs vs Pittsburgh Pirates is scheduled for Sep 11 at 02:21 PM ET.

More MLB picks

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    Fri, Sep 11
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    Fri, Sep 11
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    Fri, Sep 11
  • Tampa Bay Rays vs Houston Astros
    Fri, Sep 11
See all MLB picks →
4

Expert Picks Available

Professional handicappers have analyzed this game

Betting Odds

Chicago Cubs logoChicago Cubs
Pittsburgh PiratesPittsburgh Pirates logo
Spread
-1.50
+102
1.50
-122
Moneyline
-189
FAV
+170
Total (O/U 8.50)
Over
-110
Under
-110
GameAdvisers logo

Expert sports betting picks and predictions

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© 2026 GameAdvisers. All rights reserved.

21+Bet responsibly. Picks are for entertainment — gambling involves risk.

GameAdvisers may earn a commission from sportsbook partners linked from this site. Picks and editorial content are produced independently of any partnership. Affiliate Disclosure

Please gamble responsibly. If you have a gambling problem, please visit ncpgambling.org