Sports Pick Spread
#11 ROI: 22.06%

Calvin King

Handicapper

95 Picks R: W58 L34 P3
%W 0.61% | Streak 4
L10: W7 L3 P0
NFL finished San Francisco @ Minnesota
MINNESOTA -6 (-105)
WIN
Sports Pick Spread
#38 ROI: 12.09%

Tom Stryker

Handicapper

260 Picks R: W155 L101 P4
%W 0.60% | Streak 2
L10: W7 L3 P0
NFL finished San Francisco @ Minnesota
MINNESOTA -6 (-106)
Analysis

No Analisys Provided

WIN
Sports Pick Spread
#64 ROI: 8.03%

Colin Cowherd'...

Handicapper

96 Picks R: W53 L41 P2
%W 0.55% | Streak 0
L10: W4 L6 P0
NFL finished San Francisco @ Minnesota
MINNESOTA -6 (-110)
Analysis

No Analisys Provided

WIN
Sports Pick Spread
#94 ROI: 3.67%

Goodfella 'pre-...

HANDICAPPER

497 Picks R: W283 L209 P5
%W 0.57% | Streak 0
L10: W7 L3 P0
NFL finished San Francisco @ Minnesota
MINNESOTA -6.5 (-110)
Analysis

No Analisys Provided

WIN
Sports Pick Spread
#101 ROI: 3.49%

Bob Balfe Sport...

HANDICAPPER

232 Picks R: W124 L104 P4
%W 0.53% | Streak 6
L10: W9 L1 P0
NFL finished San Francisco @ Minnesota
MINNESOTA -6 (-105)
Analysis

No Analisys Provided

WIN
Service Play Spread
#109 ROI: 2.71%

Josh Nagel

HANDICAPPER

589 Picks R: W307 L276 P6
%W 0.52% | Streak 0
L10: W2 L8 P0
NFL finished San Francisco @ Minnesota
SAN FRANCISCO +6 (-102)
Analysis

There is no part of me that believes in Jimmy Garoppolo -- at least to the extent that 49ers fans appear to. In six games with San Francisco last year, he threw seven touchdowns and five picks. Candidly, I'm surprised this is not a touchdown spread with the Vikings at home and Mike Zimmer basically getting all offseason to game plan for Week 1. The 24-10 ATS mark at home is not lost on me, and neither is a strong Vikings defense that should help them earn a clean win to open the season. Let's also not forget who the 49ers just lost on offense.

LOSE
Sports Pick Spread
#113 ROI: 2.49%

Teddy Covers

HANDICAPPER

224 Picks R: W116 L100 P8
%W 0.52% | Streak 0
L10: W5 L4 P1
NFL finished San Francisco @ Minnesota
MINNESOTA -6 (-115)
Analysis

No Analisys Provided

WIN
Sports Pick Spread
#119 ROI: 1.89%

Dave Cokin

HANDICAPPER

322 Picks R: W168 L145 P9
%W 0.52% | Streak 0
L10: W4 L6 P0
NFL finished San Francisco @ Minnesota
SAN FRANCISCO +6.5 (-105)
Analysis

No Analisys Provided

LOSE
Sports Pick Spread
#124 ROI: 1.42%

Northcoast -

Handicapper

655 Picks R: W340 L300 P15
%W 0.52% | Streak 0
L10: W7 L3 P0
NFL finished San Francisco @ Minnesota
MINNESOTA -6 (-106)
Analysis

No Analisys Provided

WIN
Service Play Spread
#137 ROI: -0.2%

Larry Hartstei...

HANDICAPPER

1413 Picks R: W722 L668 P23
%W 0.51% | Streak 2
L10: W5 L5 P0
NFL finished San Francisco @ Minnesota
MINNESOTA -6 (-105)
Analysis

This line should be 7, and I won't be surprised if it gets there by kickoff. While I normally hate laying big points in Week 1, it's warranted in this case. 

WIN
Service Play Over Under
#162 ROI: -1.75%

Mike Tierney 't...

HANDICAPPER

770 Picks R: W384 L363 P23
%W 0.50% | Streak 0
L10: W2 L8 P0
NFL finished San Francisco @ Minnesota
UNDER 46 (-115)
Analysis

Now we'll see how good the newly anointed one, 49ers quarterback Jimmy Garoppolo, really is. The test in Minnesota was already daunting, what with the Vikes having yielded a mere 12.5 points per game at home last season. 

WIN
Sports Pick
#172 ROI: -2.49%

Maddux Sports

HANDICAPPER

575 Picks R: W289 L276 P10
%W 0.50% | Streak 3
L10: W8 L2 P0
NFL finished San Francisco @ Minnesota
SAN FRANCISCO U 8.5 -155
Analysis

No Analisys Provided

Sports Pick Spread
#187 ROI: -3.2%

The Real Swoop

Handicapper

135 Picks R: W66 L65 P4
%W 0.49% | Streak 0
L10: W4 L6 P0
NFL finished San Francisco @ Minnesota
MINNESOTA -6 (-110)
Analysis

No Analisys Provided

WIN
Service Play Spread
#191 ROI: -3.58%

R.j. White 'sta...

HANDICAPPER

548 Picks R: W266 L265 P17
%W 0.49% | Streak 2
L10: W3 L7 P0
NFL finished San Francisco @ Minnesota
MINNESOTA -6.5 (-115)
Analysis
Not a believer in the 49ers defense, especially with Reuben Foster out and several key defensive linemen dealing with injuries in the preseason.
WIN
Sports Pick Spread
#200 ROI: -3.98%

Harry Bondi

HANDICAPPER

286 Picks R: W142 L140 P4
%W 0.50% | Streak 0
L10: W6 L4 P0
NFL finished San Francisco @ Minnesota
MINNESOTA -6 (-110)
Analysis

No Analisys Provided

WIN
Service Play Spread
#202 ROI: -4.03%

Adam Thompson

Handicapper

719 Picks R: W359 L349 P11
%W 0.50% | Streak 0
L10: W4 L6 P0
NFL finished San Francisco @ Minnesota
MINNESOTA -6.5 (-110)
Analysis
The 49ers were a different team last year when Jimmy Garoppolo took over at QB. But that was 2017 and this is 2018. Teams now have enough footage to gameplan the heck out of him, and that starts Sunday against the NFL's most-dominant defense. Minnesota's offense is loaded at the skill positions, and San Francisco doesn't have the tools to fully exploit the Vikings' big weakness (O-line).
WIN
Service Play Spread
#218 ROI: -5.19%

Adam Silverste...

Handicapper

258 Picks R: W121 L124 P13
%W 0.47% | Streak 0
L10: W4 L6 P0
NFL finished San Francisco @ Minnesota
MINNESOTA -6 (-108)
Analysis

There is no part of me that believes in Jimmy Garoppolo -- at least to the extent that 49ers fans appear to. In six games with San Francisco last year, he threw seven touchdowns and five picks. Candidly, I'm surprised this is not a touchdown spread with the Vikings at home and Mike Zimmer basically getting all offseason to game plan for Week 1. The 24-10 ATS mark at home is not lost on me, and neither is a strong Vikings defense that should help them earn a clean win to open the season. Let's also not forget who the 49ers just lost on offense.

WIN
Sports Pick Spread
#232 ROI: -6.09%

Ricky Tran

Handicapper

46 Picks R: W22 L23 P1
%W 0.48% | Streak 0
L10: W6 L4 P0
NFL finished San Francisco @ Minnesota
MINNESOTA -5.5 (-120)
Analysis

No Analisys Provided

WIN
Sports Pick Spread
#243 ROI: -7%

Ferrall -

Handicapper

449 Picks R: W238 L208 P3
%W 0.53% | Streak 2
L10: W7 L3 P0
NFL finished San Francisco @ Minnesota
MINNESOTA -6 (-105)
Analysis

No Analisys Provided

WIN
Service Play Spread
#244 ROI: -7.04%

Micah Roberts

HANDICAPPER

1237 Picks R: W576 L624 P37
%W 0.47% | Streak 0
L10: W6 L4 P0
NFL finished San Francisco @ Minnesota
MINNESOTA -6.5 (-108)
Analysis

The secret to Mike Zimmer's success (44-21 ATS) entering his fifth season has been a conservative offense. It's part of the reason I don't like the move to get Kirk Cousins. But the home-field edge is huge in Minnesota and its defense is the best.

WIN
Sports Pick Spread
#251 ROI: -7.53%

Jack Jones

HANDICAPPER

671 Picks R: W315 L339 P17
%W 0.47% | Streak 2
L10: W3 L7 P0
NFL finished San Francisco @ Minnesota
SAN FRANCISCO +6.5 (-102)
Analysis

Admittedly, the Minnesota Vikings have been one of my favorite teams to back ever since Mike Zimmer took over.  They have made me a lot of money.  But they were usually in the underdog or small favorite role over the past few seasons. 

LOSE
Sports Pick
#301 ROI: -12.56%

Kenny Walker

Handicapper

140 Picks R: W64 L76 P0
%W 0.46% | Streak 1
L10: W5 L5 P0
NFL finished San Francisco @ Minnesota
SAN FRANCISCO +7 - 110
Analysis

No Analisys Provided

Sports Pick Spread
#308 ROI: -13.58%

Pointwise Plays

Handicapper

283 Picks R: W127 L149 P7
%W 0.45% | Streak 0
L10: W5 L5 P0
NFL finished San Francisco @ Minnesota
MINNESOTA -6 (-100)
Analysis

No Analisys Provided

WIN
Sports Pick Spread
#322 ROI: -16%

Millionaire's C...

HANDICAPPER

116 Picks R: W49 L63 P4
%W 0.42% | Streak 0
L10: W4 L6 P0
NFL finished San Francisco @ Minnesota
MINNESOTA -6 (-111)
Analysis

No Analisys Provided

WIN
Sports Pick Spread
#332 ROI: -17.47%

The Sports Repo...

Handicapper

51 Picks R: W22 L29 P0
%W 0.43% | Streak 1
L10: W4 L6 P0
NFL finished San Francisco @ Minnesota
MINNESOTA -6 (-110)
Analysis

No Analisys Provided

WIN
Sports Pick Spread
#333 ROI: -17.58%

Mike Missanelli

Handicapper

59 Picks R: W25 L33 P1
%W 0.42% | Streak 1
L10: W4 L6 P0
NFL finished San Francisco @ Minnesota
MINNESOTA -6 (-110)
Analysis

No Analisys Provided

WIN
Sports Pick
#340 ROI: -19.21%

Bryan Leonard

HANDICAPPER

43 Picks R: W18 L25 P0
%W 0.42% | Streak 0
L10: W4 L6 P0
NFL finished San Francisco @ Minnesota
MINNESOTA -4.5
Analysis

No Analisys Provided

Sports Pick
#364 ROI: -26.88%

Vegasdatabase -

Handicapper

35 Picks R: W14 L21 P0
%W 0.40% | Streak 0
L10: W4 L6 P0
NFL finished San Francisco @ Minnesota
U 48
Analysis

No Analisys Provided

San Francisco 49ers last injuries

Raheem Mostert

Forearm
Out indefinitely | out

Mostert will miss an extended period after undergoing a second procedure to fix his broken forearm.

Jimmy Garoppolo

Knee
Ques Week 1 | questionable

Garoppolo is recovering from a torn left ACL, and it is unknown if he will be ready to play in the season opener against the Buccaneers.

Jimmie Ward

Collarbone
Prob Week 1 | probable

Ward broke his collarbone during the offseason, but it is anticipated that he will be active Week 1 against the Buccaneers, provided no setbacks occur.

Kyle Nelson

Suspension
Elig Week 7 | out

Nelson has six games remaining on his current 10-game suspension for violating the league's policy on performance-enhancing drugs. He will be eligible to take the field against the Panthers in Week 7.